Allele Biotechnology

01/16/2026

Article about the big picture of 3D-bioprinting transplantable human organ from stem cells that Allele Biotech is a major part of now:

By reprogramming a patient’s own cells into functional tissue, this multi-year research program aims to eliminate organ waitlists and the need for lifelong anti-rejection drugs forever.

09/08/2025

This method can quickly identify high-affinity binders like antibodies, with the choice of the candidate pool size to fit the specific need. ,

San Diego, CA — Allele Biotechnology & Pharmaceuticals, Inc. (Allele), a San Diego-based biotechnology company and the first US company to have worked on the development of camelid antibodies, today announced the issuance of U.S. Patent No. 12,404,552 by the United States Patent and Trademark Offi...

05/24/2024

To realize the great potential of induced Pluripotent Stem Cells (iPSCs), start with good iPSCs reprogrammed to completion, or RE-reprogram the iPSCs you have made your favorite edits and transgenes with the Allele's mRNA method so that the iPSCs can passage well into the billions on a manufacturing site without any spontaneous differentiation or crashing. We and our pharma partners have compared our mRNA iPSC vs the other line(s) going around, the answer is simple--don't waste time with well-known, cheaply available, but incompletely reprogrammed "iPSCs".
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Allele will provide CIRM grantees with priority access to Allele’s mRNA reprogrammed cGMP iPSC lines, mRNA technologies for reprogramming, differentiation, gene editing, and end-to-end cell therapy CDMO services.   Allele Biotechnology & Pharmaceuticals Inc. (ALLELE), a San Diego, CA, based bioph...

03/04/2024

The prevalence of certain psychiatric and neurological disorders in men and women can vary significantly, here is maybe why...

We’re living in an especially promising time for biomedical discovery and advances in the delivery of data-driven health care for everyone. A key part of this is the tremendous progress made in app…

01/25/2024

https://www.youtube.com/watch?v=XqtUns2fmJs

🚀 Discover the ultimate solution to enhance your cell therapy endeavors – starting with the right iPSC line. Allele Biotech's cutting-edge approach involves...

01/17/2024

Cellular Logistics, Allele Biotech Enter into cGMP iPSC Collaboration
https://bioforward.org/2024/01/11/cellular-logistics-allele-biotech-enter-into-collaboration/
More at http://allelebiotech.com
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01/16/2024

New--changes in intrinsic gene expression levels in pancreatic beta cells (not in other cells, nor amino acid-coding mutations) cause early T2D, as described in the recent full Nature article highlighted in this NIH Director's Blog:

https://directorsblog.nih.gov/2024/01/04/uncovering-disease-driving-events-that-lead-to-type-2-diabetes/

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Nearly 35 million people in communities all across the U.S. have type 2 diabetes (T2D), putting them at increased risk for a wide range of serious health complications, including vision loss, kidne…

01/11/2024

Allele announces the partnership with Cellular Logistics, a Univ. Wisconsin-Madison spin-off that works on iPSC-derived heart tissues, project funded by NIH, https://www.allelebiotech.com/allele-and-cellular-logistics-collaborate-on-nih-funded-cell-therapy-development/

Allele cGMP single cell sorting, editing, testing, banking, https://www.allelebiotech.com/technologies/

11/07/2023

A perfect match for Allele's , figuratively and practically (say FRET!), companies can license both for best , , and quantitative !

10/10/2023

Nobel Prize on mRNA, congrats to the winners!! Just timely, Allele Biotech CEO is moderating a special subject event for San Diego Entrepreneurs Exchange (SDEE), will also present how to use mRNA to direct cell fate for cell therapy, e.g. Allele's own iPSC-beta islet work.