08/25/2026
L5–S1 is one of the most commonly affected levels in degenerative lumbar spine disease. In the population-based Wakayama Spine Study, MRI-defined intervertebral disc degeneration at L5–S1 was observed in 66.7% of men and 70.9% of women, second in frequency only to L4–L5.¹ Lumbar spinal stenosis is also frequently observed at the lumbosacral level. In a study of 121 patients with clinical symptoms of lateral lumbar spinal stenosis, 43.0% demonstrated grade 2 lateral recess stenosis and 62.0% demonstrated grade 2 foraminal stenosis at L5–S1.² Together, these findings underscore the clinical importance of L5–S1 in degenerative lumbar pathology. The Aurora Spine ZIP™ MIS Interspinous Fusion System provides posterior, non-pedicle supplemental fixation of the non-cervical spine from T1–S1. ZIP is FDA-cleared for supplemental fusion in patients with degenerative disc disease, lumbar spinal stenosis, spondylolisthesis, trauma and/or tumor.³
References
Teraguchi M, et al. Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: The Wakayama Spine Study. Osteoarthritis and Cartilage. 2014;22(1):104–110.
Norisyam Y, et al. Lateral Lumbar Spinal Stenosis: Associations With the Oswestry Disability Index, Visual Analogue Scale, and Magnetic Resonance Imaging. 2023.
Aurora Spine, Inc. ZIP™ MIS Interspinous Fusion System. FDA 510(k) K221399. Cleared July 8, 2022.