FC-BIOS

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FC-BIOS This sites is to connect the Malaysian scientific community with our partners worldwide.

Founded in 1989, today has over 50 employees with its head office located 20 minute by road from our capital city Kuala Lumpur. Our dedicated staff members together with loyal Partners bring leading edge technologies and products for the Industrial, Clinical and Academic R&D facilities in Malaysia. Our team of professional sales representatives are backed by our technical support personnel should a question arise about any product or applications. A dedicated team of service engineers provides aftersales service.

2005 saw 2 key mile stone in our expansion. The first being the FC-Bios, Penang branch office to enhance our sales and support to customers in the Northern region and the Customer Training Centre in our head office to conduct technical seminars and training workshops for our valued customers. With these initiatives combined with strategic marketing and alliances with new partners FC-Bios remains customers’ number one source and solution provider to their ever demanding Laboratory, Process, Safety and Environment application needs.

Your tubes are sterile. Your RT-qPCR is still failing on nuclease contamination — and the certificate on the box was nev...
16/10/2026

Your tubes are sterile. Your RT-qPCR is still failing on nuclease contamination — and the certificate on the box was never going to tell you otherwise.

Sterile, RNase-free, endotoxin-free and non-cytotoxic are four separate lot attributes. Not a ladder. Four different tests.

→ Sterile means no viable organisms. Gamma irradiation kills organisms; it does not reliably denature a robust RNase. A sterile tube can carry active nuclease and still be labelled correctly.

→ RNase/DNase-free is a separate certificate. It says that lot was tested for those nucleases. It says nothing about sterility — and for most RT-qPCR work sterility is irrelevant while nuclease contamination is fatal.

→ Endotoxin survives sterilisation. Bacterial lipopolysaccharide is not alive, so killing the bacteria that produced it does not remove it. Pyrogen-free is the attribute that decides cell culture work.

→ SAL 10⁻⁶ is a probability, not a promise. No more than one unit in a million is expected to carry a viable organism. A statistical claim about a validated process — not a guarantee about the tube in your hand.

The practical map: cell culture needs sterile, non-cytotoxic and endotoxin-free. RT-qPCR needs RNase-free. Microbiology needs sterile.

Ask for the attribute your application actually needs, and ask to see it on the certificate of analysis rather than the catalogue page.

FC-BIOS is the authorised distributor for Corning and Sorfa cell-culture plasticware, and for Tarsons pipette tips and centrifuge tubes, in Malaysia.
WhatsApp/Call 019-220 8238 · [email protected] · www.fcbios.com.my

Full explainer: https://www.fcbios.com.my/blogs/news-insight/sterile-laboratory-plasticware-what-does-it-mean

Is every autoclave load in your lab truly sterile, and can you prove it?Join the FC-BIOS Webinar Series for "Principles ...
16/10/2026

Is every autoclave load in your lab truly sterile, and can you prove it?

Join the FC-BIOS Webinar Series for "Principles and Practice of Steam Sterilization", a practical session on running, verifying and documenting steam sterilization in the laboratory.

What you'll learn:
✅ Specialized sterilization cycles and when to use them
✅ Validation and monitoring protocols
✅ Operational best practices and loading techniques
✅ Live Q&A with our team

📅 Wednesday, 28 October 2026 | 🕙 10:00 AM MYT | 💻 Online via Demio

Register now: https://my.demio.com/ref/WrleQFLYBppdKfkK

Your rotor is rated. Your tube is rated too — separately, by a different manufacturer, on a different test. Most protoco...
14/10/2026

Your rotor is rated. Your tube is rated too — separately, by a different manufacturer, on a different test. Most protocols only check one of them.

Here is how far apart two tubes of the same size can sit.

In one manufacturer's catalogue, the 15 mL conical in polypropylene is rated to 18,000 × g. The 15 mL conical in polystyrene — same volume, same catalogue — is rated to 3,500 × g. Five times apart, on a difference you cannot see across a bench.

Volume tells you nothing. The resin and the moulding set the number.

Then the part that surprises people: the rating assumes support.

It holds in a properly matched adapter or bucket that carries the tube wall. Catalogues often print a bare maximum with no rotor named, so ask which configuration it was tested in. A conical loose in an oversized bucket is not that configuration, and the rating does not follow it there.

The rating also falls over a tube's life, and nothing on the label tells you:

→ Prior autoclaving
→ Hairline cracks from an earlier spin
→ Chemical attack from solvents or strong bases
→ Cold embrittlement

None of it is visible until the tube fails.

And that last one deserves its own line. Polypropylene goes brittle at around 0 °C — which is exactly why frozen tubes shatter when they are handled roughly or dropped into a rotor. Let them come up, or handle them as though they were glass.

The rotor is rated. The tube is rated separately. Match them.

FC-BIOS is the authorised distributor for Tarsons, Corning, LP ITALIANA and Sorfa centrifuge tubes and vials in Malaysia, and for Gyrozen centrifuges.

Send us the g-force your protocol needs and we will match the tube to it.

WhatsApp/Call 019-220 8238
[email protected]
www.fcbios.com.my

Your plate reader does one of three things. Your assay needs a particular one, and no setting in the software changes wh...
12/10/2026

Your plate reader does one of three things. Your assay needs a particular one, and no setting in the software changes which.

Absorbance, fluorescence and luminescence are three different light paths through the same instrument — not three modes of the same measurement.

→ Absorbance measures what gets through. Light goes in one side of the well, the detector reads what comes out, and the number is a ratio rather than a signal. ELISA, protein quantification and cell viability all run on it. Thermo's Multiskan SkyHigh is an absorbance instrument — it reads a well's full 200–1,000 nm spectrum in under ten seconds.

→ Fluorescence has to excite first. You supply the excitation light and read a longer wavelength coming back. Two wavelengths to select, and a choice most people skip: read from the top of the well, or through the bottom. Varioskan LUX selects both with monochromators and offers top and bottom reading.

→ Luminescence has no excitation at all. The reaction makes its own photons — ATP assays, reporter genes. Nothing is excited, so there is no excitation path to set. The whole problem becomes collecting the few photons you have.

And the part that is not on the instrument at all: the plate is part of the optical system. Plate colour is specified by detection mode, not by preference.

→ Clear for absorbance — light has to pass through
→ Black for fluorescence — the walls absorb stray excitation and cut well-to-well crosstalk
→ White for luminescence — the walls reflect emitted photons back towards the detector

Run a fluorescent assay in a clear plate and the reader is not what failed.

A detection mode is optics. Check which modes your assay needs before you check the price.

FC-BIOS is the authorised distributor for Thermo Fisher microplate readers in Malaysia — Varioskan LUX, Varioskan ALF, Multiskan SkyHigh and Multiskan FC.
WhatsApp/Call 019-220 8238 · [email protected] · www.fcbios.com.my

Sources: Thermo Fisher Scientific product specifications · Promega, plate selection guidance

The bottle that keeps your bench safe is the one destroying your rotor.Eppendorf names chlorite-ion solutions — sodium h...
09/10/2026

The bottle that keeps your bench safe is the one destroying your rotor.

Eppendorf names chlorite-ion solutions — sodium hypochlorite, ordinary bleach — as the single most frequent cause of rotor corrosion. Not an occasional cause. The most frequent one. And it is the disinfectant in most laboratories, because it is cheap and it works.

Anodised aluminium has a protective oxide layer. Chlorite ions take that layer off. What is underneath corrodes.

The exclusion list is longer than bleach, and every item is already in your building: acetone, caustic solutions, dishwasher detergent, steel wool, wire brushes.

What to use instead takes two minutes.

→ Neutral detergent or 70% isopropanol
→ Rinse with distilled water, then dry
→ Glycerol on the O-rings so they stay pliable instead of going brittle

Then the part almost nobody does: look inside the tube bores. Corrosion starts as pitting in there, out of sight, and you will not find it unless you go looking. Pits become holes — and a rotor that fails at full speed is not a maintenance problem, it is a safety incident.

The question for your next lab meeting is not whether your rotors are clean. It is what they are being cleaned with, and who decided that.

FC-BIOS is the authorised distributor for Gyrozen in Malaysia, and supplies replacement rotors and aerosol-tight lids.
WhatsApp/Call 019-220 8238 · [email protected] · www.fcbios.com.my

Source: Eppendorf rotor care guidance

Two tubes filled to the same mark, in opposite positions. That is not a balanced load.Balance is a mass problem. The rot...
07/10/2026

Two tubes filled to the same mark, in opposite positions. That is not a balanced load.

Balance is a mass problem. The rotor responds to what is on the scale — not to what is printed on the side of the tube. INTEGRA puts it plainly: a tube of density gradient medium against a tube of water at the same volume is an imbalance. Same graduation, different densities. Weigh them.

Three things follow.

→ Empty bucket, fine. Missing bucket, never. The rotor is balanced as a mechanical assembly, with every bucket in place, loaded or empty. Removing one changes the mass distribution of the rotor itself — a different failure, and a more serious one.

→ Symmetry, twice over. Across the centre of rotation, so opposite positions match. And across each bucket's own pivot axis, so the bucket swings level. Beckman notes that buckets which fail to reach full horizontal give poor separations. Imbalance is not only a machine that shakes.

→ The odd number problem. Three tubes sit at 120° to each other. Five in a six-place rotor takes a mass-matched blank in the sixth. Never make up the difference by eye. A blank costs one tube and thirty seconds; deceleration in a tilted bucket can re-mix what you just sedimented.

Balance is a mass problem with a geometry constraint. Neither half is optional.

FC-BIOS is the authorised distributor for Gyrozen centrifuges in Malaysia.
WhatsApp/Call 019-220 8238 · [email protected] · www.fcbios.com.my

Sources: INTEGRA Biosciences · Beckman Coulter

⏰ Final call! Our Cold Chain Monitoring webinar is this Wednesday, 7 Oct.📅 Wed, 7 Oct 2026 | 🕙 10:00 AM MYT | 💻 DemioLea...
05/10/2026

⏰ Final call! Our Cold Chain Monitoring webinar is this Wednesday, 7 Oct.

📅 Wed, 7 Oct 2026 | 🕙 10:00 AM MYT | 💻 Demio

Learn how monitoring gadgets keep your temperature records audit-ready and stop excursions before they cost you product.

👉 Last chance to register: https://my.demio.com/ref/E2Duv0MhStAMHcjg

Two rotors, same machine, same speed — and the pellet ends up somewhere different.A fixed-angle rotor holds tubes at 25–...
05/10/2026

Two rotors, same machine, same speed — and the pellet ends up somewhere different.

A fixed-angle rotor holds tubes at 25–45°. The path to the tube wall is short, so pelleting is fast and the achievable g is high. The pellet forms against the side of the tube, part way up.

A swing-out rotor's buckets rotate to horizontal under load. Sedimentation is radial, so the pellet lands at the very bottom. Maximum g is lower — but the pellet is compact and resuspends in a minimal volume.

And two jobs belong to the swing-out alone. Density gradients need their layers horizontal; a fixed angle tilts them and they smear on deceleration. Microplates need to sit flat. Neither is a preference — a fixed-angle rotor simply cannot do them.

The decision in one line:

→ Pellet hard, pellet fast, discard the supernatant: fixed-angle.
→ Plates, gradients, or a pellet you have to resuspend cleanly: swing-out.

Buying one rotor for a machine several teams share? Ask which of those two your users actually do before you choose. The answer is often both.

FC-BIOS is the authorised distributor for Gyrozen centrifuges in Malaysia.
WhatsApp/Call 019-220 8238 · [email protected] · www.fcbios.com.my

Sources: Eppendorf Lab Academy · Beckman Coulter rotor documentation

[FC-BIOS Workshop] Antiphospholipid Syndrome: Strengthening Diagnosis from ELISA to CLIA26 September 2026 · Spectrum Roo...
02/10/2026

[FC-BIOS Workshop] Antiphospholipid Syndrome: Strengthening Diagnosis from ELISA to CLIA
26 September 2026 · Spectrum Room, Nexus @ Connexion, Kuala Lumpur

Around 40 of you gave up a Saturday for this one. Thank you.

Rheumatologists, pathologists, microbiologists, haematology medical officers, laboratory managers and medical laboratory scientists — from government and university hospitals, private hospital groups and reference laboratories. Doors at 9.30, last session closed at 4.30.

What we covered:

✅ APS — the local landscape · Assoc. Prof. Dr. Nurasyikin Yusof, HCTM UKM
✅ Setting the baseline — method comparison of aPL testing in Malaysia · Dr. Samitaa Rajendiran, FC-BIOS
✅ HCTM–FC-BIOS research collaboration — likelihood-ratio thresholds, and aPL in pathological pregnancies · Dr. Khamsatun Ramlan and Dr. Mohamad Saiful Ridzuan, HCTM UKM
✅ From ELISA to CLIA: a diagnostic transition journey · Mr. Kunasilan A/L Sundra Raju, Premier Integrated Labs
✅ YHLO innovations · Prof. Edward Zheng, International Chief Scientist, YHLO Biotech

Three things that came up across the sessions:

→ The ELISA numbers do not travel. 40 and 80 GPL/MPL were never built for automated chemiluminescence, and values move with platform and calibration. Err either way and the patient pays — anticoagulation that was not needed, or a missed thromboprophylaxis opportunity.

→ One cut-off throws away the gradient. Positive or negative discards the information in how positive. Interval-specific likelihood ratios keep it as low, medium and high (Devreese, Vandevelde et al., Thrombosis and Haemostasis, 2024).

→ Much of the fix sits upstream of the analyser. The biggest source of wasted aPL testing raised on the day was the request form — aCL ordered as part of a connective tissue screen, with no clinical features of APS.

And one line worth carrying back to the bench: "borderline" is not a result. Report it inconclusive, retest, and remember classification still needs persistence confirmed twelve weeks later.

To everyone who presented, and to YHLO Biotech for running the day with us — thank you. Missed it? Message us and we will send you the session summary.

FC-BIOS is the authorised distributor for YHLO in Malaysia.
WhatsApp/Call 019-220 8238 · [email protected] · www.fcbios.com.my

Your SOP says 10,000 rpm. The lab down the corridor runs the same 10,000 rpm and gets a different result. Neither of you...
02/10/2026

Your SOP says 10,000 rpm. The lab down the corridor runs the same 10,000 rpm and gets a different result. Neither of you is doing anything wrong.

The dial reads rpm. The sample feels g. What separates them is the rotor.

RCF = 1.118 × 10⁻⁵ × r × RPM², with r in centimetres. The radius is in the equation and speed is squared.

Thermo's worked figure makes it concrete: 5,000 rpm on a rotor of 7 cm radius gives 1,957 × g. Put that same 5,000 rpm on a 10 cm rotor and you are near 2,800 × g. Same number on the dial. Forty-three percent more force on the pellet.

Which is why an rpm protocol does not travel. "10,000 × g for 10 minutes" means the same thing on both machines. Publish the g.

And r is not one number. r_max is the bottom of the tube, where the pellet forms; r_min is the meniscus. Different machines report different radii — know which one yours displays before you compare anything.

Convert once, write it down, and the protocol travels.

FC-BIOS is the authorised distributor for Gyrozen centrifuges in Malaysia.
WhatsApp/Call 019-220 8238 · [email protected] · www.fcbios.com.my

Source: Thermo Fisher Scientific TR0040

Address

31 & 33, Jalan SS 15/4B
Subang Jaya
47500

Opening Hours

Monday 09:00 - 18:00
Tuesday 09:00 - 18:00
Wednesday 09:00 - 18:00
Thursday 09:00 - 18:00
Friday 09:00 - 18:00

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+60192208238

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