27/04/2026
من MAXXEUS الممبرين الوحيد في العالم و الأغرب في تصنيعه حيث يأتي من الكيس اللي بيكون فيه الجنين أثناء الحمل
Composition
BioXclude is composed of allograft amnion and chorion tissue. These layers represent the inner and outermost layers of the amniotic membrane, the only barrier between the mother and fetus, protecting both from each other's immune systems and infection. It also serves as a shock absorber, prevents adhesion, and regulates fetal temperature. Amnion tissue is rich in collagen types III, IV, and VI. Chorion tissue consists of a reticular layer, a basement membrane containing a layer of dense connective tissue, and a trophoblast layer. The reticular and basement membrane layers contain collagen types I, III, IV, V, and VI.10
A Paradigm Shift in Resorption Kinetics
BioXclude jump-starts the natural wound healing process. It allows for rapid gingival epithelial cell migration and promotes neovascularization, enabling the rapid establishment of blood supply by activating the migration of human mesenchymal and hematopoietic stem cells. BioXclude stimulates the proliferation and migration of human microvascular endothelial cells and causes these cells to produce and release angiogenic growth factors. The high concentration of Laminin-5 provides an ideal substrate for the attachment of gingival epithelial cells and Directly Attached Tooth (DAT) cells, which supports why BioXclude may be placed over exposed roots and is safe to leave exposed. BioXclude resorbs in 8–12 weeks, as demonstrated with histology.17 BioXclude is truly a paradigm shift in resorption kinetics It is a bioactive barrier, recruiting mesenchymal stem cells to the site, which differentiate between hard and soft tissues before the matrix resorbs. Once this process begins, a faster resorption profile is ideal, allowing the periosteum to take over. This process challenges established theories regarding barrier membrane characteristics, which have been based solely on an inert scaffold …